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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2A
All Species:
8.79
Human Site:
S48
Identified Species:
12.89
UniProt:
P13861
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13861
NP_004148.1
404
45518
S48
R
E
A
R
A
P
A
S
V
L
P
A
A
T
P
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
G106
Q
Q
E
N
E
R
K
G
T
A
R
F
G
H
E
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
G87
Q
Q
E
N
E
R
K
G
T
A
R
F
G
H
E
Dog
Lupus familis
XP_541890
401
45078
S48
R
E
A
R
L
Q
A
S
S
P
P
A
A
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P12367
401
45371
S47
R
E
A
R
R
Q
E
S
D
T
F
I
V
S
P
Rat
Rattus norvegicus
P12368
401
45522
S48
R
E
A
R
R
Q
E
S
D
S
F
I
A
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
V20
L
D
F
I
D
L
G
V
C
A
E
A
Y
N
P
Chicken
Gallus gallus
Q5ZM91
382
43332
P46
C
T
V
R
P
D
R
P
M
G
F
L
R
E
Y
Frog
Xenopus laevis
NP_001084637
402
45172
A47
K
Q
S
Q
S
Q
G
A
P
F
S
H
G
M
G
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
G47
R
D
T
R
S
Q
D
G
S
G
A
A
A
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
S53
Q
S
E
R
P
S
V
S
H
T
D
Q
S
T
D
Honey Bee
Apis mellifera
XP_392905
383
43849
L54
R
E
S
R
Q
T
Q
L
I
Q
D
P
A
Q
T
Nematode Worm
Caenorhab. elegans
P30625
366
41449
L45
P
D
N
P
V
L
F
L
K
D
H
F
E
K
L
Sea Urchin
Strong. purpuratus
Q26619
369
41770
G47
Q
E
N
N
I
S
L
G
G
K
R
G
V
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
R80
Q
S
A
Q
S
Q
S
R
S
R
S
S
V
M
F
Red Bread Mold
Neurospora crassa
Q01386
385
42138
F57
K
N
N
A
A
P
A
F
W
N
G
F
G
G
D
Conservation
Percent
Protein Identity:
100
58.4
61.1
91
N.A.
86.8
86.8
N.A.
58.6
35.1
64.8
71.2
N.A.
48.7
49.7
32.9
52.2
Protein Similarity:
100
68.3
70.7
94.5
N.A.
91.3
92
N.A.
69
52.7
80.6
83.6
N.A.
67.8
69
54.9
69
P-Site Identity:
100
0
0
66.6
N.A.
40
46.6
N.A.
13.3
6.6
0
26.6
N.A.
20
26.6
0
13.3
P-Site Similarity:
100
13.3
13.3
66.6
N.A.
46.6
46.6
N.A.
20
13.3
40
40
N.A.
33.3
40
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.2
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
32
7
13
0
19
7
0
19
7
25
32
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
7
7
7
0
13
7
13
0
0
0
13
% D
% Glu:
0
38
19
0
13
0
13
0
0
0
7
0
7
7
13
% E
% Phe:
0
0
7
0
0
0
7
7
0
7
19
25
0
0
13
% F
% Gly:
0
0
0
0
0
0
13
25
7
13
7
7
25
7
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
7
0
13
0
% H
% Ile:
0
0
0
7
7
0
0
0
7
0
0
13
0
0
0
% I
% Lys:
13
0
0
0
0
0
13
0
7
7
0
0
0
13
0
% K
% Leu:
7
0
0
0
7
13
7
13
0
7
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
13
0
% M
% Asn:
0
7
19
19
0
0
0
0
0
7
0
0
0
7
0
% N
% Pro:
7
0
0
7
13
13
0
7
7
7
13
7
0
13
32
% P
% Gln:
32
19
0
13
7
38
7
0
0
7
0
7
0
7
0
% Q
% Arg:
38
0
0
50
13
13
7
7
0
7
19
0
7
0
0
% R
% Ser:
0
13
13
0
19
13
7
32
19
7
13
7
7
7
0
% S
% Thr:
0
7
7
0
0
7
0
0
13
13
0
0
0
19
13
% T
% Val:
0
0
7
0
7
0
7
7
7
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _